SCHEMBL8489013

SCHEMBL8489013

CCCCCCC(CC)=NO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.44
CES1 P23141 3/20 0.44
GPR84 Q9NQS5 7/20 0.42
PPARG P37231 7/20 0.42
PPARD Q03181 7/20 0.42
PPARA Q07869 7/20 0.42
TSHR P16473 6/20 0.42
HDAC11 Q96DB2 5/20 0.42
PTPN1 P18031 3/20 0.42
ALDH1A1 P00352 3/20 0.42
TLR2 O60603 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
FABP4 P15090 2/20 0.42
SLC22A6 Q4U2R8 1/20 0.42
SLC22A8 Q8TCC7 1/20 0.42
MEN1 O00255 1/20 0.42
ESR1 P03372 1/20 0.42
ALOX15 P16050 1/20 0.42
PDE4A P27815 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9669201 1.00 CES2 (0.44) CES2CES1GPR84PPARGPPARD
SCHEMBL11881637 1.00 CES2 (0.44) CES2CES1GPR84PPARGPPARD
SCHEMBL8632750 1.00 CES2 (0.44) CES2CES1GPR84PPARGPPARD
SCHEMBL11881632 1.00 CES2 (0.44) CES2CES1GPR84PPARGPPARD
SCHEMBL10970511 1.00 CES2 (0.44) CES2CES1GPR84PPARGPPARD
SCHEMBL8632755 1.00 CES2 (0.44) CES2CES1GPR84PPARGPPARD
SCHEMBL8489012 1.00 CES2 (0.44) CES2CES1GPR84PPARGPPARD
SCHEMBL9669195 1.00 CES2 (0.44) CES2CES1GPR84PPARGPPARD
SCHEMBL22115590 1.00 CES2 (0.44) CES2CES1GPR84PPARGPPARD
SCHEMBL167678 0.97 CES2 (0.42) CES2CES1GPR84PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2575451-A1 COMPOUNDS, METHODS, AND DEVICES FOR DETECTING AND/OR TREATING INSECT INFESTATION Bayer Cropscience LP (US) 2013-04-10 EP claimed
CN-103025157-A Compounds, methods, and devices for detecting and/or treating insect infestation BAYER CROPSCIENCE LP 2013-04-03 CN claimed
WO-2011149901-A1 COMPOUNDS, METHODS, AND DEVICES FOR DETECTING AND/OR TREATING INSECT INFESTATION BAYER CROPSCIENCE LP (US) 2011-12-01 WO claimed
US-5412006-A Electrorheological cels and a method for the preparation thereof DOW CORNING CORPORATION (US) 1995-05-02 US claimed
EP-4499414-A1 FILM, FILM-COATED OBJECT AND METHOD FOR PRODUCING A FILM-COATED OBJECT LEONHARD KURZ Stiftung & Co. KG (DE) 2025-02-05 EP disclosed
EP-3668721-B1 METHOD FOR PRODUCING A FILM-COATED ARTICLE AND FILM-COATED ARTICLE LEONHARD KURZ STIFTUNG & CO KG (DE) 2024-05-29 EP disclosed
EP-3740206-B1 INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) SYROS PHARMACEUTICALS INC (US) 2024-03-06 EP disclosed
US-11918592-B2 Inhibitors of cyclin dependent kinase 7 (CDK7) SYROS PHARMACEUTICALS, INC. (US) 2024-03-05 US disclosed
WO-2023186460-A1 FILM, FILM-COATED OBJECT AND METHOD FOR PRODUCING A FILM-COATED OBJECT LEONHARD KURZ STIFTUNG & CO. KG (DE) 2023-10-05 WO disclosed
US-11679619-B2 Transfer film, method for producing a film-coated article and film-coated article LEONHARD KURZ STIFTUNG & CO. KG (DE) 2023-06-20 US disclosed
US-20220000890-A1 INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) MEDIC LIFE SCIENCES, INC. 2022-01-06 US disclosed
EP-3740206-A1 INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) Syros Pharmaceuticals, Inc. (US) 2020-11-25 EP disclosed
US-20110293553-A1 IDENTIFICATION OF INSECT ATTRACTANT, ARRESTING, AND/OR AGGREGATION COMPOUNDS AND METHODS THEREOF UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2011-12-01 US disclosed
US-5856489-A Process for the production of aminoazobicycloalkanes from oximes SMITHKLINE BEECHAM P.L.C. (GB) 1999-01-05 US disclosed
EP-0672745-B1 Electrorheological gels and method for preparation DOW CORNING (US) 1998-02-25 EP disclosed
EP-0672745-A2 Electrorheological gels and method for preparation DOW CORNING CORPORATION (US) 1995-09-20 EP disclosed
US-5412006-A Electrorheological cels and a method for the preparation thereof DOW CORNING CORPORATION (US) 1995-05-02 US disclosed
US-5073233-A METHOD OF MAKING A METALLIC PATTERN ON A SUBSTRATE CIBA-GEIGY CORPORATION (US) 1991-12-17 US disclosed
EP-0402315-A2 A method of making a metallic pattern on a substrate CIBA-GEIGY AG (CH) 1990-12-12 EP disclosed
US-4424213-A PESTICIDES SDS BIOTECH CORPORATION (US) 1984-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220000890-A1 INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) CDK7, CDK3, CCNK CES2 4661/4885CES1 3746/4885GPR84 2809/4885
US-20110293553-A1 IDENTIFICATION OF INSECT ATTRACTANT, ARRESTING, AND/OR AGGREGATION COMPOUNDS AND METHODS THEREOF L3MBTL3, ATG13, ARRB1 CES2 1736/4885CES1 2486/4885GPR84 2007/4885
US-11918592-B2 Inhibitors of cyclin dependent kinase 7 (CDK7) CDK7, CDK3, CCNK CES2 4661/4885CES1 3746/4885GPR84 2809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.