Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489148 | 0.90 | GAA (0.52) | GAANPSR1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL5734450 | 0.89 | POLB (0.41) | GAANPSR1POLBALDH1A1SMN1; SMN2 | |
| Bromide SCHEMBL5734269 | 0.88 | POLB (0.41) | GAANPSR1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7427899 | 0.88 | POLB (0.41) | GAANPSR1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8485814 | 0.87 | GAA (0.43) | GAANPSR1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8485856 | 0.82 | GAA (0.43) | GAANPSR1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9300884 | 0.82 | POLB (0.47) | GAANPSR1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8490703 | 0.81 | SMN1; SMN2 (0.43) | GAANPSR1POLBALDH1A1SMN1; SMN2 | |
| Benzoic Acid SCHEMBL8489705 | 0.80 | ALDH1A1 (0.40) | GAANPSR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9299066 | 0.80 | POLB (0.43) | GAANPSR1POLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955463-A | ANTITUMOR, ANTIINFLAMMATORY, AND ANTIARTHRITIC AGENTS | ZENECA LIMITED (GB) | 1999-09-21 | — | — | US | disclosed |