Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HAT1 | O14929 | 1/20 | 0.36 |
| ▸ | KAT7 | O95251 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | RBBP7 | Q16576 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | EIF4EBP1 | Q13541 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489042 | 0.90 | GAA (0.40) | GAAPOLBNPSR1ALDH1A1TNF | |
| SCHEMBL5734450 | 0.79 | POLB (0.41) | GAAPOLBNPSR1ALDH1A1TNF | |
| SCHEMBL8489146 | 0.78 | SMN1; SMN2 (0.31) | GAAPOLBNPSR1ALDH1A1MAPT | |
| SCHEMBL7427899 | 0.78 | POLB (0.41) | GAAPOLBNPSR1ALDH1A1TNF | |
| Bromide SCHEMBL5734269 | 0.78 | POLB (0.41) | GAAPOLBNPSR1ALDH1A1TNF | |
| SCHEMBL8485814 | 0.76 | GAA (0.43) | GAAPOLBNPSR1ALDH1A1TNF | |
| SCHEMBL8485856 | 0.72 | GAA (0.43) | GAAPOLBNPSR1ALDH1A1TNF | |
| Benzoic Acid SCHEMBL8489705 | 0.71 | ALDH1A1 (0.40) | GAANPSR1EIF4EBP1ALDH1A1MAPT | |
| SCHEMBL9300884 | 0.71 | POLB (0.47) | GAAPOLBNPSR1ALDH1A1TNF | |
| SCHEMBL8490703 | 0.70 | SMN1; SMN2 (0.43) | GAAPOLBNPSR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955463-A | ANTITUMOR, ANTIINFLAMMATORY, AND ANTIARTHRITIC AGENTS | ZENECA LIMITED (GB) | 1999-09-21 | — | — | US | disclosed |