Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 7/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.45 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 9/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 7/20 | 0.36 |
| ▸ | HTR2B | P41595 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489075 | 0.83 | MTNR1B (0.56) | SLC9A1MTNR1BSLC9A5SLC9A2HTR2A | |
| SCHEMBL19699401 | 0.81 | SLC9A1 (0.52) | SLC9A1MTNR1BSLC9A5SLC9A2HTR2A | |
| SCHEMBL6682308 | 0.81 | SLC9A1 (0.52) | SLC9A1MTNR1BSLC9A5SLC9A2HTR2A | |
| SCHEMBL6678123 | 0.81 | SLC9A1 (0.52) | SLC9A1MTNR1BSLC9A5SLC9A2HTR2A | |
| SCHEMBL6681968 | 0.80 | MTNR1B (0.64) | SLC9A1MTNR1BSLC9A5SLC9A2HTR2A | |
| SCHEMBL7701623 | 0.80 | MTNR1B (0.64) | SLC9A1MTNR1BSLC9A5SLC9A2HTR2A | |
| SCHEMBL19699403 | 0.80 | MTNR1B (0.64) | SLC9A1MTNR1BSLC9A5SLC9A2HTR2A | |
| SCHEMBL6680857 | 0.80 | MTNR1B (0.64) | SLC9A1MTNR1BSLC9A5SLC9A2HTR2A | |
| SCHEMBL6682129 | 0.79 | MTNR1B (0.59) | SLC9A1MTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL17020523 | 0.79 | MTNR1B (0.59) | SLC9A1MTNR1BHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856529-A | ADJUSTMENT OF NERVOUS SYSTEM, ENDOCRINE FUNCTION; REPRODUCTION, BODY WEIGHT AND METABOLISM | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-05 | — | — | US | disclosed |