Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.59 |
| ▸ | RAB9A | P51151 | 9/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 3/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3585730 | 0.86 | POLB (0.55) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL11566043 | 0.76 | GRM5 (0.60) | NPC1RAB9ASMN1; SMN2KDM4EKMT2A | |
| SCHEMBL3639088 | 0.76 | FAAH (0.60) | NPC1RAB9ASMN1; SMN2NPY5RKMT2A | |
| SCHEMBL27657075 | 0.76 | KMT2A (0.83) | NPC1RAB9ASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL28409561 | 0.75 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2KDM4EKMT2A | |
| SCHEMBL4927932 | 0.74 | HDAC1 (0.66) | NPC1RAB9ASMN1; SMN2NPY5RFAAH | |
| SCHEMBL3764185 | 0.74 | FAAH (0.71) | FAAH | |
| SCHEMBL28056008 | 0.74 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL4079342 | 0.74 | TSHR (0.69) | NPC1RAB9ASMN1; SMN2KDM4EKMT2A | |
| SCHEMBL16585513 | 0.74 | TRPV1 (0.59) | NPC1RAB9ASMN1; SMN2KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021835-A1 | QUINOLINE DERIVATIVES AS H+-ATPase INHIBITORS AND AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |