Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1846269 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL4947382 | 0.84 | MAPT (0.34) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL172419 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL2904103 | 0.81 | KMT2A (0.36) | ALDH1A1KMT2AMAPTKDM4EHPGD | |
| SCHEMBL1134463 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL29258046 | 0.76 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL15236783 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL321283 | 0.74 | TLR4 (0.52) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL12606807 | 0.74 | TLR4 (0.52) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9793537 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968908-A | Restricted 9-cis retinoids | AMERICAN CYANAMID COMPANY (US) | 1999-10-19 | — | — | US | disclosed |
| US-5064826-A | Analgesic, antiderpressant | EGIS GYOGYSZERGYAR (HU) | 1991-11-12 | — | — | US | disclosed |
| US-3972880-A | TRANQUILIZER | SHARPS ASSOCIATES (US) | 1976-08-03 | — | — | US | disclosed |
| US-3960871-A | ANTIDEPRESSANT, ANALGESICS, ANTICONVULSANT ANTI-ANXIETY ACTIVITY | SHARPS ASSOCIATES (US) | 1976-06-01 | — | — | US | disclosed |
| US-3940421-A | Intermediates for the preparation of thienobenzopyrans and thiopyranobenzopyrans | ARTHUR D. LITTLE, INC. (US) | 1976-02-24 | — | — | US | disclosed |