Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 2/20 | 0.39 |
| ▸ | FLT4 | P35916 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486154 | 0.90 | NPC1 (0.47) | TRPV1KDRNPSR1LMNAPOLB | |
| SCHEMBL8490721 | 0.90 | TRPV1 (0.43) | TRPV1PTGER3NPSR1LMNAPOLB | |
| SCHEMBL8489178 | 0.89 | MAPT (0.45) | TRPV1NPSR1LMNAPOLBTYK2 | |
| SCHEMBL8486434 | 0.89 | SMN1; SMN2 (0.47) | TRPV1PTGER3NPSR1LMNAPOLB | |
| SCHEMBL8486703 | 0.86 | NPSR1 (0.46) | TRPV1KDRNPSR1LMNAPOLB | |
| SCHEMBL8487940 | 0.86 | HTT (0.52) | NPSR1LMNATYK2 | |
| SCHEMBL8486950 | 0.85 | KMT2A (0.48) | TRPV1POLBTYK2JAK2JAK1 | |
| SCHEMBL8487714 | 0.85 | NPSR1 (0.44) | TRPV1NPSR1POLBTYK2JAK2 | |
| SCHEMBL8584811 | 0.84 | TRPV1 (0.50) | TRPV1NPSR1LMNAPOLB | |
| SCHEMBL8490225 | 0.84 | TYK2 (0.41) | KDRNPSR1LMNAPOLBTYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021835-A1 | QUINOLINE DERIVATIVES AS H+-ATPase INHIBITORS AND AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |