Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488438 | 0.91 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EMEN1POLB | |
| SCHEMBL8485126 | 0.90 | KMT2A (0.42) | ALDH1A1KMT2AKDM4EMEN1POLB | |
| SCHEMBL8489290 | 0.82 | KMT2A (0.36) | ALDH1A1KMT2AKDM4EMEN1POLB | |
| SCHEMBL8485123 | 0.80 | KMT2A (0.38) | ALDH1A1KMT2AKDM4EMEN1POLB | |
| SCHEMBL8489294 | 0.80 | NAMPT (0.36) | ALDH1A1KMT2AKDM4EMEN1POLB | |
| SCHEMBL8488360 | 0.77 | NAMPT (0.40) | ALDH1A1KMT2AKDM4EMEN1POLB | |
| SCHEMBL8485127 | 0.77 | EIF4EBP1 (0.34) | ALDH1A1KMT2AKDM4EMEN1POLB | |
| SCHEMBL7427899 | 0.75 | POLB (0.41) | ALDH1A1KMT2AKDM4EMEN1POLB | |
| SCHEMBL8488436 | 0.74 | NAMPT (0.40) | ALDH1A1KMT2AKDM4EMEN1POLB | |
| SCHEMBL9299312 | 0.74 | TYMS (0.46) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955463-A | ANTITUMOR, ANTIINFLAMMATORY, AND ANTIARTHRITIC AGENTS | ZENECA LIMITED (GB) | 1999-09-21 | — | — | US | disclosed |