Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885756 | 0.89 | ALDH1A1 (0.33) | DHODHSLC6A3POLBLMNASMN1; SMN2 | |
| SCHEMBL8492585 | 0.87 | PDE2A (0.32) | DHODHMEN1KMT2A | |
| SCHEMBL8491946 | 0.85 | DHODH (0.33) | DHODHNR1H4ALDH1A1 | |
| SCHEMBL7924451 | 0.85 | DHODH (0.34) | DHODHLMNAEPHX2GAAMEN1 | |
| SCHEMBL8488330 | 0.84 | PDE2A (0.36) | DHODHLMNASMN1; SMN2EPHX2MEN1 | |
| SCHEMBL9115094 | 0.84 | DHODH (0.34) | DHODHLMNAGAAMEN1KMT2A | |
| SCHEMBL8729870 | 0.83 | DHODH (0.33) | DHODHNR1H4ALDH1A1MEN1KMT2A | |
| SCHEMBL9116308 | 0.83 | DHODH (0.33) | DHODHLMNAMEN1KMT2ANPC1 | |
| SCHEMBL8492875 | 0.83 | DHODH (0.35) | DHODHLMNAEPHX2MEN1KMT2A | |
| SCHEMBL8492877 | 0.83 | NR1H4 (0.33) | DHODHLMNANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1057524-C | Herbicides | RHONE POULENC AGROCH (GB) | 2000-10-18 | — | — | CN | claimed |
| EP-0560482-B1 | 4-Benzoyl isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-08-06 | — | — | EP | claimed |
| EP-0560482-A1 | 4-Benzoyl isoxazoles derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-09-15 | — | — | EP | claimed |
| CN-1076194-A | Weedicide | RHONE POULENC AGRICULTURE (GB) | 1993-09-15 | — | — | CN | claimed |
| CN-1057524-C | Herbicides | RHONE POULENC AGROCH (GB) | 2000-10-18 | — | — | CN | disclosed |
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| EP-0560482-B1 | 4-Benzoyl isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-08-06 | — | — | EP | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| EP-0560482-A1 | 4-Benzoyl isoxazoles derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-09-15 | — | — | EP | disclosed |