Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489351 | 0.89 | DHODH (0.36) | ALDH1A1LMNAPOLBDHODHSLC6A3 | |
| SCHEMBL8491586 | 0.87 | ALDH1A1 (0.35) | ALDH1A1LMNAPOLBDHODHSLC6A2 | |
| SCHEMBL8887759 | 0.87 | DHODH (0.35) | ALDH1A1DHODHSMN1; SMN2NR1H4EPHX2 | |
| SCHEMBL9114255 | 0.86 | SLC6A2 (0.35) | ALDH1A1LMNAPOLBDHODHSLC6A2 | |
| SCHEMBL8889888 | 0.85 | DHODH (0.32) | ALDH1A1DHODHSMN1; SMN2EPHX2 | |
| SCHEMBL9116568 | 0.84 | DHODH (0.31) | DHODHNR1H4 | |
| SCHEMBL8492585 | 0.84 | PDE2A (0.32) | DHODH | |
| SCHEMBL8886439 | 0.83 | ALDH1A1 (0.33) | ALDH1A1LMNAPOLBDHODHSLC6A2 | |
| SCHEMBL8494384 | 0.83 | SMYD3 (0.41) | ALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL7924451 | 0.82 | DHODH (0.34) | LMNADHODHEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |