Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488506 | 0.84 | G6PD (0.36) | KDM4ETDP1PARP1ELANEG6PD | |
| SCHEMBL8485962 | 0.80 | NPC1 (0.39) | KDM4EPIK3CAMTORNPC1RAB9A | |
| SCHEMBL8486440 | 0.75 | KDM4E (0.36) | KDM4ETDP1PARP1PIK3CAMTOR | |
| SCHEMBL8489309 | 0.69 | KDM4E (0.39) | KDM4ETDP1PARP1ELANEG6PD | |
| SCHEMBL6537761 | 0.69 | KMT2A (0.53) | KDM4ENPC1RAB9AKMT2AGAA | |
| SCHEMBL6538159 | 0.68 | TDP1 (0.46) | KDM4ETDP1PARP1ELANEG6PD | |
| SCHEMBL8488066 | 0.68 | GCK (0.39) | KDM4ETDP1PARP1 | |
| SCHEMBL18436321 | 0.66 | PARP1 (0.42) | KDM4EPARP1ELANENPC1RAB9A | |
| SCHEMBL8489999 | 0.65 | ABL1 (0.38) | — | |
| SCHEMBL8489156 | 0.65 | KDM4E (0.39) | KDM4EKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021835-A1 | QUINOLINE DERIVATIVES AS H+-ATPase INHIBITORS AND AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |