SCHEMBL8489644

SCHEMBL8489644

O=C1N=NCN1Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.45
CRBN Q96SW2 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
F2 P00734 1/20 0.44
PLG P00747 1/20 0.44
ELANE P08246 1/20 0.44
CTSG P08311 1/20 0.44
CMA1 P23946 1/20 0.44
CTRC Q99895 1/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
POLB P06746 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
GAA P10253 2/20 0.42
EPHX2 P34913 1/20 0.41
GSK3A P49840 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4101769 0.72 DDB1 (0.46) DDB1CRBNL3MBTL1F2PLG
SCHEMBL4892237 0.70 EPHX2 (0.45) DDB1CRBNL3MBTL1F2PLG
SCHEMBL5251526 0.70 DDB1 (0.49) DDB1CRBNL3MBTL1F2PLG
SCHEMBL29450073 0.70 KMT2A (0.76) DDB1CRBNL3MBTL1F2PLG
SCHEMBL11052192 0.70 KMT2A (0.59) DDB1CRBNL3MBTL1F2PLG
SCHEMBL16416392 0.70 KMT2A (0.76) DDB1CRBNL3MBTL1F2PLG
SCHEMBL1488276 0.70 L3MBTL1 (0.56) DDB1CRBNL3MBTL1F2PLG
SCHEMBL6855500 0.68 DDB1 (0.54) DDB1CRBNL3MBTL1F2PLG
SCHEMBL5982177 0.68 L3MBTL1 (0.54) DDB1CRBNL3MBTL1F2PLG
SCHEMBL7389188 0.67 L3MBTL1 (0.73) DDB1CRBNL3MBTL1F2PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999007687-A1 PESTICIDAL 4-BENZYL-1,2,4-TRIAZOLIN-5-ONE DERIVATIVES AGREVO UK LIMITED (GB) 1999-02-18 WO disclosed