Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4154502 | 0.84 | ERCC1 (0.43) | KMT2AMEN1DRD3KCNH2SMN1; SMN2 | |
| SCHEMBL11848182 | 0.82 | SMN1; SMN2 (0.47) | KMT2AMEN1POLBSMN1; SMN2TSHR | |
| SCHEMBL6858115 | 0.82 | KMT2A (0.44) | EPHX2L3MBTL1DDB1CRBNF2 | |
| SCHEMBL6855500 | 0.82 | DDB1 (0.54) | L3MBTL1DDB1CRBNF2PLG | |
| SCHEMBL4133922 | 0.80 | DRD2 (0.49) | KMT2AMEN1POLBCYP2D6CYP2C19 | |
| SCHEMBL3451882 | 0.77 | SIGMAR1 (0.54) | L3MBTL1F2PLGELANECTSG | |
| SCHEMBL4137157 | 0.76 | ALDH1A1 (0.53) | L3MBTL1KMT2AMEN1POLBCYP2D6 | |
| SCHEMBL4151283 | 0.76 | ALDH1A1 (0.41) | L3MBTL1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL10417429 | 0.75 | L3MBTL1 (0.48) | EPHX2L3MBTL1DDB1CRBNF2 | |
| SCHEMBL7745544 | 0.75 | EPHX2 (0.46) | EPHX2L3MBTL1DDB1CRBNF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153639-B2 | Silver halide color photographic lightsensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2006-12-26 | — | — | US | claimed |
| US-7004979-B2 | Dyeing composition comprising at least one diaminopyrazole oxidation base and at least one pyrazolo-azole coupling agent | L'OREAL S.A. (FR) | 2006-02-28 | — | — | US | claimed |
| US-20040237220-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base and a pyrazolo-azole coupling agent | L'OREAL S.A. (FR) | 2004-12-02 | — | — | US | claimed |
| US-20040161713-A1 | Silver halide color photographic lightsensitive material | FUJIFILM CORPORATION (JP) | 2004-08-19 | — | — | US | claimed |
| EP-0891181-B1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-AZOLE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | OREAL (FR) | 2003-05-14 | — | — | EP | claimed |
| US-6551360-B2 | Pyrazoline-3,5-dione-containing compositions for dyeing keratin fibres; their use in dyeing as couplers; dyeing process | VIDAL LAURENT (FR) | 2003-04-22 | — | — | US | claimed |
| EP-0929286-B1 | COMPOSITIONS FOR DYEING KERATIN FIBRES CONTAINING S-OXIDE-THIAZOLO-AZOLES AND/OR S,S-DIOXIDE-THIAZOLO-AZOLES; THEIR USE FOR DYEING AS COUPLERS, METHOD OF DYEING | OREAL (FR) | 2002-10-23 | — | — | EP | claimed |
| EP-0889718-B1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING PYRROLO-AZOLE COMPOUNDS, USE THEREOF AS COUPLERS, AND DYEING METHOD | OREAL (FR) | 2002-09-18 | — | — | EP | claimed |
| EP-0900074-B1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING PYRAZOLIN-3,5-DIONE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | OREAL (FR) | 2002-05-15 | — | — | EP | claimed |
| US-6379395-B1 | DYEING FOR HAIR DYE | L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| US-6210447-B1 | APPLYING AT LEAST ONE DYEING FORMULATION CONTAINING A COUPLER CHOSEN FROM A PYRAZOLINE-3,5-DIONE COMPOUND AND SALT AND AN OXIDATION BASE TO KERATIN FIBERS, DEVELOPING A COLOR AT ACIDIC, NEUTRAL OR BASIC PH IN PRESENCE OF AN OXIDIZING AGNET | L'OREAL (FR) | 2001-04-03 | — | — | US | claimed |
| US-6179882-B1 | OXIDATION COLOR DYES | L'OREAL (FR) | 2001-01-30 | — | — | US | claimed |
| US-6165229-A | Imidazoloazole-containing compositions for dyeing keratin fibers; their use in dyeing as couplers; dyeing process | L'OREAL (FR) | 2000-12-26 | — | — | US | claimed |
| US-6139589-A | HAIR DYES | L'OREAL S.A. (FR) | 2000-10-31 | — | — | US | claimed |
| EP-0888109-B1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-PYRIMIDINEOXO COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHODS | OREAL (FR) | 2000-08-30 | — | — | EP | claimed |
| US-6063136-A | Compositions containing pyrrolo-oxazole couplers for dyeing keratin fibers and dyeing methods | L'OREAL S.A. (FR) | 2000-05-16 | — | — | US | claimed |
| EP-0893985-B1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING IMIDAZOLO-AZOLE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | OREAL (FR) | 2000-04-12 | — | — | EP | claimed |
| EP-0447920-B1 | Silver halide color photographic material | FUJI PHOTO FILM CO LTD (JP) | 1996-02-07 | — | — | EP | claimed |
| US-5194369-A | Heterocyclic diamides as couplers | FUJI PHOTO FILM CO., LTD. (JP) | 1993-03-16 | — | — | US | claimed |
| EP-0447920-A1 | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-09-25 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040237220-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base and a pyrazolo-azole coupling agent | KRT18, PPOX, NOX5 | EPHX2 1314/4885L3MBTL1 4885/4885DDB1 735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.