SCHEMBL8489672

SCHEMBL8489672

Cc1cnc(C2CCNCC2)[nH]1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 2/20 0.48
PARP1 P09874 3/20 0.39
HTR2C P28335 6/20 0.39
HRH3 Q9Y5N1 1/20 0.39
TLR9 Q9NR96 1/20 0.38
TLR8 Q9NR97 1/20 0.38
TLR7 Q9NYK1 1/20 0.38
KHK P50053 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
HRH4 Q9H3N8 1/20 0.36
SLC18A3 Q16572 1/20 0.35
SIGMAR1 Q99720 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL22468947 0.98 HPGDS (0.47) HPGDSPARP1HTR2CHRH3TLR9
SCHEMBL14488002 0.88
SCHEMBL19862537 0.84 NPC1 (0.40) HPGDS
SCHEMBL6633135 0.82 NPC1 (0.42) HPGDS
SCHEMBL22860618 0.78 PARP1 (0.44) HPGDSPARP1HRH3TLR9TLR8
SCHEMBL17001709 0.77 HPGDS (0.48) HPGDSPARP1HRH3TLR9TLR8
Bromide SCHEMBL16992466 0.76 HPGDS (0.47) HPGDSPARP1HRH3TLR9TLR8
SCHEMBL28643814 0.73 TLR8 (0.37) HPGDSPARP1TLR8TLR7
SCHEMBL18845575 0.70 HPGDS (0.81) HPGDSHTR2CTLR9TLR8TLR7
SCHEMBL47075 0.70 CHRM2 (0.41) PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112250837-B Bio-based furan epoxy resin and method for preparing bio-based furan epoxy resin by thermal curing of solvent-free anhydride 南京先进生物材料与过程装备研究院有限公司 2023-05-05 CN claimed
CN-112250837-A Bio-based furan epoxy resin and method for preparing bio-based furan epoxy resin through solvent-free anhydride thermosetting 南京先进生物材料与过程装备研究院有限公司 2021-01-22 CN claimed
US-20250179046-A1 SEROTONIN 5-HT2B INHIBITORY COMPOUNDS ZOETIS SERVICES LLC 2025-06-05 US disclosed
US-12240827-B2 Serotonin 5-HT2B inhibitory compounds ZOETIS SERVICES LLC (US) 2025-03-04 US disclosed
EP-3947360-B1 SEROTONIN 5-HT2B INHIBITORY COMPOUNDS ZOETIS SERVICES LLC (US) 2024-08-07 EP disclosed
CN-113631548-B Serotonin 5-HT2B inhibiting compounds 硕腾服务有限责任公司 2023-06-06 CN disclosed
CN-112250837-B Bio-based furan epoxy resin and method for preparing bio-based furan epoxy resin by thermal curing of solvent-free anhydride 南京先进生物材料与过程装备研究院有限公司 2023-05-05 CN disclosed
US-20220162183-A1 SEROTONIN 5-HT2B INHIBITORY COMPOUNDS ZOETIS SERVICES LLC 2022-05-26 US disclosed
EP-3947360-A1 SEROTONIN 5-HT2B INHIBITORY COMPOUNDS Zoetis Services LLC (US) 2022-02-09 EP disclosed
CN-113631548-A Serotonin 5-HT2B inhibiting compounds 硕腾服务有限责任公司 2021-11-09 CN disclosed
CN-112250837-A Bio-based furan epoxy resin and method for preparing bio-based furan epoxy resin through solvent-free anhydride thermosetting 南京先进生物材料与过程装备研究院有限公司 2021-01-22 CN disclosed
WO-2021003314-A1 HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS NUVATION BIO INC. (US) 2021-01-07 WO disclosed
WO-2020198478-A1 SEROTONIN 5-HT2B INHIBITORY COMPOUNDS ZOETIS SERVICES LLC (US) 2020-10-01 WO disclosed
WO-1999006377-A1 DERIVATIVES OF 1-((3,3-DIMETHYL-3-SILABUTOXY)METHYL)-2-(PHENYLSULFONYL)IMIDAZOLE GLIATECH, INC. (US) 1999-02-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12240827-B2 Serotonin 5-HT2B inhibitory compounds HTR2B, HTR1B, HTR5A HPGDS 1202/4885PARP1 4048/4885HTR2C 10/4885
US-20220162183-A1 SEROTONIN 5-HT2B INHIBITORY COMPOUNDS HTR2B, HTR1B, HTR5A HPGDS 1202/4885PARP1 4048/4885HTR2C 10/4885
US-20250179046-A1 SEROTONIN 5-HT2B INHIBITORY COMPOUNDS HTR2B, HTR1B, HTR5A HPGDS 1202/4885PARP1 4048/4885HTR2C 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.