Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966322 | 1.00 | POLB (0.36) | POLBL3MBTL1LMNAKDM4EALDH1A1 | |
| SCHEMBL31122224 | 0.89 | POLB (0.38) | POLBKDM4EALDH1A1SMN1; SMN2NAPRT | |
| SCHEMBL6743153 | 0.82 | L3MBTL1 (0.43) | L3MBTL1LMNAKDM4ETDP1 | |
| SCHEMBL6743645 | 0.82 | L3MBTL1 (0.43) | L3MBTL1LMNAKDM4ETDP1 | |
| SCHEMBL29386641 | 0.82 | L3MBTL1 (0.43) | L3MBTL1LMNAKDM4ETDP1 | |
| SCHEMBL6744312 | 0.82 | L3MBTL1 (0.43) | L3MBTL1LMNAKDM4ETDP1 | |
| SCHEMBL5596018 | 0.82 | L3MBTL1 (0.43) | L3MBTL1LMNAKDM4ETDP1 | |
| SCHEMBL6740171 | 0.82 | L3MBTL1 (0.43) | L3MBTL1LMNAKDM4ETDP1 | |
| SCHEMBL6740419 | 0.82 | L3MBTL1 (0.43) | L3MBTL1LMNAKDM4ETDP1 | |
| SCHEMBL6741431 | 0.82 | L3MBTL1 (0.43) | L3MBTL1LMNAKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003838-A1 | 2-(1,2,3,4-TETRAHYDROXYBUTYL)PYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | disclosed |
| WO-1999003838-A1 | 2-(1,2,3,4-TETRAHYDROXYBUTYL)PYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | disclosed |