Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11201848 | 0.87 | ATM (1.00) | ATMSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL5925536 | 0.86 | ATM (0.77) | ATMSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL2821475 | 0.86 | ATM (0.77) | ATMSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL11081554 | 0.86 | ATM (0.97) | ATMSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL8489898 | 0.86 | ATM (0.77) | ATMSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL24177773 | 0.86 | ATM (0.77) | ATMSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL501720 | 0.85 | ATM (0.76) | ATMSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL14369836 | 0.84 | ATM (0.75) | ATMSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL10174568 | 0.84 | ATM (0.75) | ATMSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL5350446 | 0.84 | ATM (0.74) | ATMSMN1; SMN2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863913-A | ALLEVIATION OF RENAL DYSFUNCTION WITHOUT AFFECTING BLOOD PRESSURE AT A LOW BLOOD CONCENTRATION. | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1999-01-26 | — | — | US | disclosed |