Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | IDE | P14735 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | PNLIP | P16233 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490063 | 0.84 | PTGS1 (0.32) | PTGS1ALOX5MAPTKMT2APOLB | |
| SCHEMBL5266203 | 0.78 | ALOX5 (0.41) | PTGS1ALOX5MAPTKMT2APOLB | |
| SCHEMBL9321549 | 0.77 | ALOX5 (0.58) | PTGS1ALOX5MAPTKMT2APOLB | |
| SCHEMBL9285268 | 0.74 | LMNA (0.55) | ALOX5MAPTKMT2AMEN1LMNA | |
| SCHEMBL21931411 | 0.74 | LMNA (0.55) | ALOX5MAPTKMT2AMEN1LMNA | |
| SCHEMBL21929591 | 0.74 | LMNA (0.55) | ALOX5MAPTKMT2AMEN1LMNA | |
| SCHEMBL21929589 | 0.74 | LMNA (0.55) | ALOX5MAPTKMT2AMEN1LMNA | |
| SCHEMBL21131789 | 0.74 | LMNA (0.55) | ALOX5MAPTKMT2AMEN1LMNA | |
| SCHEMBL21931412 | 0.74 | LMNA (0.55) | ALOX5MAPTKMT2AMEN1LMNA | |
| SCHEMBL8187742 | 0.71 | KMT2A (0.37) | MAPTKMT2APOLBGAAIDE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999006392-A1 | METHOD FOR PREPARING 2H-1 BENZOPYRANES AND SYNTHESIS INTERMEDIATES | RHODIA CHIMIE (FR) | 1999-02-11 | — | — | WO | disclosed |