Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 11/20 | 0.50 |
| ▸ | HSD11B2 | P80365 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.43 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29607150 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TSHRHSD11B1HSD11B2SMN1; SMN2 | |
| SCHEMBL4679326 | 0.77 | ALDH1A1 (0.67) | ALDH1A1TSHRHSD11B1HSD11B2SMN1; SMN2 | |
| SCHEMBL30060822 | 0.76 | ALDH1A1 (0.55) | ALDH1A1TSHRHSD11B1HSD11B2SMN1; SMN2 | |
| SCHEMBL2124587 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL22468368 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL2124591 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL25501601 | 0.74 | ALDH1A1 (0.63) | ALDH1A1TSHRHSD11B1HSD11B2SMN1; SMN2 | |
| SCHEMBL27024183 | 0.74 | ALDH1A1 (0.63) | ALDH1A1TSHRHSD11B1HSD11B2SMN1; SMN2 | |
| SCHEMBL14197780 | 0.73 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD11B1HSD11B2SMN1; SMN2 | |
| SCHEMBL1307123 | 0.73 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD11B1HSD11B2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1707202-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2006-10-04 | — | — | EP | disclosed |