SCHEMBL8490368

SCHEMBL8490368

CCCCC(CCS)CN(C)C

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP3A4 P08684 2/20 0.37
TSHR P16473 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.35
LMNA P02545 1/20 0.33
FDPS P14324 1/20 0.32
DNM1 Q05193 5/20 0.32
CA2 P00918 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8493273 0.86 ALDH1A1 (0.38) ALDH1A1TDP1CYP3A4TSHRL3MBTL1
SCHEMBL8493312 0.86
SCHEMBL21078039 0.86 ALDH1A1 (0.41) ALDH1A1TDP1CYP3A4TSHRL3MBTL1
SCHEMBL8754719 0.85 ALDH1A1 (0.44) ALDH1A1TDP1CYP3A4TSHRL3MBTL1
SCHEMBL5192362 0.84 LMNA (0.50) ALDH1A1TDP1CYP3A4TSHRLMNA
SCHEMBL5195497 0.84 LMNA (0.50) ALDH1A1TDP1CYP3A4TSHRLMNA
SCHEMBL5197062 0.83 LMNA (0.48) ALDH1A1TDP1CYP3A4TSHRLMNA
SCHEMBL28101361 0.83 ALDH1A1 (0.46) ALDH1A1TDP1CYP3A4TSHRL3MBTL1
SCHEMBL8493318 0.83 PLA2G1B (0.42) ALDH1A1TDP1CYP3A4TSHRLMNA
SCHEMBL10666915 0.81 LMNA (0.52) TSHRLMNAFDPSDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0676237-B1 Modified ion exchange resins and use thereof MITSUBISHI CHEM CORP (JP) 1999-03-17 EP disclosed
US-5589517-A N,N-DI-SUBSTITITUTED MERCAPTOALKYLAMINE SULFONIC ACID ION EXCHANGE RESIN AS CATALYST FOR CONDENSATION REACTION OF A PHENOL AND A KETONE TO PRODUCE A BISPHENOL MITSUBISHI CHEMICAL CORPORATION (JP) 1996-12-31 US disclosed
EP-0676237-A1 Modified ion exchange resins and use thereof MITSUBISHI CHEMICAL CORPORATION (JP) 1995-10-11 EP disclosed