Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | IKBKB | O14920 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8494460 | 0.92 | ALDH1A1 (0.34) | ALDH1A1MAPK1HTTIKBKBPOLB | |
| SCHEMBL8462743 | 0.89 | GPR119 (0.33) | ALDH1A1GPR119PKMKMT2A | |
| SCHEMBL9020009 | 0.88 | IKBKB (0.37) | ALDH1A1MAPK1HTTIKBKBPOLB | |
| SCHEMBL8493609 | 0.87 | IKBKB (0.36) | ALDH1A1MAPK1HTTGPR119IKBKB | |
| SCHEMBL8493432 | 0.87 | GPR119 (0.38) | ALDH1A1GPR119PKMKMT2A | |
| SCHEMBL8491698 | 0.85 | IKBKB (0.35) | ALDH1A1MAPK1HTTGPR119IKBKB | |
| SCHEMBL7462434 | 0.81 | — | — | |
| SCHEMBL8490483 | 0.79 | HTT (0.36) | ALDH1A1HTTGPR119KMT2A | |
| SCHEMBL8492745 | 0.79 | IKBKB (0.36) | ALDH1A1MAPK1HTTIKBKBPOLB | |
| SCHEMBL8492594 | 0.78 | GPR119 (0.32) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| EP-0418175-B1 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-07-17 | — | — | EP | disclosed |
| EP-0470856-B1 | Isoxazole derivatives, process for their preparation and their herbicidal applications | RHONE POULENC AGRICULTURE (GB) | 1995-10-11 | — | — | EP | disclosed |
| EP-0470856-A1 | Isoxazole derivatives, process for their preparation and their herbicidal applications | RHONE-POULENC AGRICULTURE LTD. (GB) | 1992-02-12 | — | — | EP | disclosed |
| EP-0418175-A2 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1991-03-20 | — | — | EP | disclosed |