Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492295 | 0.76 | GID4 (0.55) | GID4L3MBTL1HTR2AHTR2CDRD3 | |
| SCHEMBL2664145 | 0.74 | GID4 (0.71) | GID4L3MBTL1DRD3MAPK1NPSR1 | |
| SCHEMBL2359018 | 0.70 | GID4 (0.71) | GID4L3MBTL1DRD3 | |
| SCHEMBL20912502 | 0.70 | GID4 (0.71) | GID4L3MBTL1DRD3 | |
| SCHEMBL20912489 | 0.70 | GID4 (0.71) | GID4L3MBTL1DRD3 | |
| SCHEMBL12760970 | 0.68 | GID4 (0.62) | GID4L3MBTL1DRD3KEAP1PNMT | |
| SCHEMBL4344185 | 0.68 | GID4 (1.00) | GID4L3MBTL1HTR2AHTR2CDRD3 | |
| SCHEMBL4353119 | 0.68 | GID4 (0.67) | GID4L3MBTL1DRD3KEAP1PNMT | |
| SCHEMBL3404796 | 0.67 | GID4 (0.57) | GID4L3MBTL1DRD3KEAP1PNMT | |
| SCHEMBL12761049 | 0.67 | GID4 (0.60) | GID4L3MBTL1HTR2CDRD3KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999045013-A1 | 4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-09-10 | — | — | WO | disclosed |