SCHEMBL8492295 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	GID4	Q8IVV7	2/20	0.55

▸	L3MBTL1	Q9Y468	1/20	0.55

▸	HTR2A	P28223	3/20	0.43

▸	HTR2C	P28335	3/20	0.43

▸	DRD3	P35462	1/20	0.42

▸	KEAP1	Q14145	1/20	0.36

▸	PNMT	P11086	1/20	0.35

▸	MEN1	O00255	1/20	0.34

▸	ALDH1A1	P00352	1/20	0.34

▸	KMT2A	Q03164	1/20	0.34

▸	MAPT	P10636	1/20	0.33

▸	SMN1; SMN2	Q16637	1/20	0.33

▸	TAAR1	Q96RJ0	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2330566	0.78	PRCP (0.57)	GID4HTR2AHTR2CMAPT
SCHEMBL29010950	0.78	PRCP (0.57)	GID4HTR2AHTR2CMAPT
SCHEMBL2359018	0.77	GID4 (0.71)	GID4L3MBTL1DRD3MEN1KMT2A
SCHEMBL20912489	0.77	GID4 (0.71)	GID4L3MBTL1DRD3MEN1KMT2A
SCHEMBL20912502	0.77	GID4 (0.71)	GID4L3MBTL1DRD3MEN1KMT2A
Hydrochloric Acid SCHEMBL30439132	0.77	GAA (0.58)	GID4HTR2AHTR2CMAPTTAAR1
Hydrochloric Acid SCHEMBL29010844	0.77	GAA (0.58)	GID4HTR2AHTR2CMAPTTAAR1
SCHEMBL8490673	0.76	GID4 (0.54)	GID4L3MBTL1HTR2AHTR2CDRD3
SCHEMBL4353119	0.75	GID4 (0.67)	GID4L3MBTL1DRD3KEAP1PNMT
SCHEMBL12761049	0.73	GID4 (0.60)	GID4L3MBTL1HTR2CDRD3KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1999045013-A1	4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES	NOVO NORDISK A/S (DK)	1999-09-10	—	—	WO	disclosed