Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 8/20 | 0.54 |
| ▸ | AURKA | O14965 | 8/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9609200 | 0.87 | RPS6KB1 (0.53) | RPS6KB1AURKAAURKBEGFRPDPK1 | |
| SCHEMBL8495218 | 0.83 | LMNA (0.60) | RPS6KB1AURKAAURKBEGFRMAPK1 | |
| SCHEMBL7498445 | 0.82 | AURKB (0.44) | RPS6KB1AURKAAURKBMAPK1SMN1; SMN2 | |
| SCHEMBL8490466 | 0.81 | RPS6KB1 (0.49) | RPS6KB1AURKAAURKBEGFRPDPK1 | |
| SCHEMBL8504575 | 0.80 | RPS6KB1 (0.46) | RPS6KB1AURKAEGFRPDPK1MAPK1 | |
| SCHEMBL9608172 | 0.80 | AURKA (0.44) | RPS6KB1AURKAAURKBEGFRPDPK1 | |
| SCHEMBL8516669 | 0.78 | RPS6KB1 (0.47) | RPS6KB1AURKAAURKBEGFRPDPK1 | |
| SCHEMBL14843414 | 0.78 | AURKA (0.46) | RPS6KB1AURKAAURKBPDPK1 | |
| SCHEMBL9921350 | 0.78 | HTT (0.58) | EGFRMAPK1LMNAHTTAPP | |
| SCHEMBL8546216 | 0.78 | AURKA (0.55) | RPS6KB1AURKAAURKBEGFRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120136150-A1 | 4-(3-Butynyl)Aminopyrimidine Derivatives as Pest Control Agents for Agricultural and Horticultural Use | SDS BIOTECH K.K. (JP) | 2012-05-31 | — | — | US | disclosed |
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136150-A1 | 4-(3-Butynyl)Aminopyrimidine Derivatives as Pest Control Agents for Agricultural and Horticultural Use | CBR3, CBR1, HRH2 | RPS6KB1 3088/4885AURKA 3468/4885AURKB 3475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.