Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 11/20 | 0.47 |
| ▸ | AURKA | O14965 | 9/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491976 | 0.86 | LPAR1 (0.45) | RPS6KB1AURKAAURKBLPAR2LPAR1 | |
| SCHEMBL12960926 | 0.85 | RPS6KB1 (0.44) | RPS6KB1AURKAAURKBLPAR2LPAR1 | |
| SCHEMBL8516838 | 0.84 | GALR3 (0.50) | RPS6KB1AURKAAURKBEGFR | |
| SCHEMBL9608199 | 0.81 | LPAR2 (0.42) | RPS6KB1AURKAAURKBLPAR2LPAR1 | |
| SCHEMBL8507035 | 0.81 | LPAR2 (0.51) | RPS6KB1AURKAAURKBLPAR2LPAR1 | |
| SCHEMBL8490854 | 0.78 | RPS6KB1 (0.54) | RPS6KB1AURKAAURKBNR1H2NR1H3 | |
| SCHEMBL8498949 | 0.78 | PDE1B (0.43) | RPS6KB1AURKAAURKBLPAR2LPAR1 | |
| SCHEMBL8516358 | 0.78 | RAB9A (0.54) | — | |
| SCHEMBL8497982 | 0.77 | LPAR1 (0.47) | RPS6KB1AURKAAURKBLPAR2LPAR1 | |
| SCHEMBL8504821 | 0.76 | LPAR2 (0.45) | RPS6KB1AURKAAURKBLPAR2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120136150-A1 | 4-(3-Butynyl)Aminopyrimidine Derivatives as Pest Control Agents for Agricultural and Horticultural Use | SDS BIOTECH K.K. (JP) | 2012-05-31 | — | — | US | disclosed |
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136150-A1 | 4-(3-Butynyl)Aminopyrimidine Derivatives as Pest Control Agents for Agricultural and Horticultural Use | CBR3, CBR1, HRH2 | RPS6KB1 3088/4885AURKA 3468/4885AURKB 3475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.