Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 3/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490985 | 1.00 | HPD (0.52) | HPDFLT1FLT4KDRMAPT | |
| SCHEMBL8488686 | 0.81 | GAA (0.66) | HPDFLT1FLT4KDRMAPT | |
| SCHEMBL8488684 | 0.81 | GAA (0.66) | HPDFLT1FLT4KDRMAPT | |
| SCHEMBL4658862 | 0.80 | HPD (0.62) | HPDFLT1FLT4KDRMAPT | |
| SCHEMBL10099704 | 0.77 | ALDH1A1 (0.49) | MAPTALDH1A1KMT2ALMNAGAA | |
| SCHEMBL18579153 | 0.76 | HPD (0.57) | HPDFLT1FLT4KDRMAPT | |
| SCHEMBL8489355 | 0.75 | HPD (0.50) | HPDFLT1FLT4KDRMAPT | |
| SCHEMBL8489357 | 0.75 | HPD (0.50) | HPDFLT1FLT4KDRMAPT | |
| SCHEMBL5452045 | 0.75 | HPD (0.60) | HPDFLT1FLT4KDRMAPT | |
| SCHEMBL442397 | 0.75 | HPD (0.60) | HPDFLT1FLT4KDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| EP-0487357-B1 | 4 Benzoyl isoxazole derivatives | RHONE POULENC AGRICULTURE (GB) | 1997-07-02 | — | — | EP | disclosed |
| EP-0487357-A1 | 4 Benzoyl isoxazole derivatives | RHONE-POULENC AGRICULTURE LTD. (GB) | 1992-05-27 | — | — | EP | disclosed |