SCHEMBL849188

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL848950	0.90	MEN1 (0.53)	MAPTMEN1KMT2AALDH1A1KDM4E
	SCHEMBL846948	0.88	PTH1R (0.43)	MEN1KMT2AALDH1A1GBA1
	SCHEMBL849240	0.87	MEN1 (0.48)	MAPTMEN1KMT2AALDH1A1KDM4E
	SCHEMBL848900	0.83	MEN1 (0.50)	TP53MEN1KMT2AALDH1A1TSHR
	SCHEMBL849742	0.83	KMT2A (0.46)	MAPTMEN1KMT2AALDH1A1LMNA
	SCHEMBL13552101	0.83	MEN1 (0.51)	MAPTMEN1KMT2AALDH1A1KDM4E
	SCHEMBL849347	0.82	MEN1 (0.50)	MAPTMEN1KMT2AALDH1A1MAPK1
	SCHEMBL847618	0.81	MEN1 (0.46)	MAPTMEN1KMT2AALDH1A1LMNA
	SCHEMBL850091	0.81	MEN1 (0.50)	MEN1KMT2AALDH1A1LMNAHTT
	SCHEMBL848912	0.80	MEN1 (0.47)	MAPTMEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.