SCHEMBL847618

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL848594	0.91	MEN1 (0.46)	MEN1KMT2AALDH1A1MGLLKDM4E
	SCHEMBL13552101	0.89	MEN1 (0.51)	MEN1KMT2AAKR1C3ALDH1A1MGLL
	SCHEMBL848950	0.87	MEN1 (0.53)	MEN1KMT2AALDH1A1MGLLKDM4E
	SCHEMBL849240	0.84	MEN1 (0.48)	MEN1KMT2AALDH1A1MGLLKDM4E
	SCHEMBL849183	0.83	TSHR (0.56)	MEN1KMT2AAKR1C3ALDH1A1LMNA
	SCHEMBL849188	0.81	MAPT (0.46)	MEN1KMT2AALDH1A1KDM4ELMNA
	SCHEMBL849281	0.81	MAPK1 (0.54)	MEN1KMT2AALDH1A1LMNAHSD17B10
	SCHEMBL848900	0.80	MEN1 (0.50)	MEN1KMT2AALDH1A1MGLLGBA1
	SCHEMBL849742	0.80	KMT2A (0.46)	MEN1KMT2AALDH1A1KDM4ELMNA
	SCHEMBL849347	0.79	MEN1 (0.50)	MEN1KMT2AALDH1A1MGLLKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.