SCHEMBL849263

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20210610	1.00	DGKA (0.55)	DGKACYP1A2ALDH1A1ALOX15TDP1
	SCHEMBL3827295	1.00	DGKA (0.55)	DGKACYP1A2ALDH1A1ALOX15TDP1
	SCHEMBL8430549	0.98	CYP1A2 (0.57)	DGKACYP1A2ALDH1A1ALOX15TDP1
	SCHEMBL21657588	0.94	CYP1A2 (0.53)	DGKACYP1A2ALDH1A1ALOX15TDP1
	SCHEMBL8193710	0.94	DGKA (0.57)	DGKACYP1A2ALDH1A1ALOX15TDP1
	SCHEMBL2943131	0.91	CYP1A2 (0.59)	DGKACYP1A2ALDH1A1ALOX15TDP1
	SCHEMBL4253773	0.90	DGKA (0.59)	DGKACYP1A2DNM1PAMPRSS1
	SCHEMBL9007977	0.89	DGKA (0.46)	DGKACYP1A2ALDH1A1ALOX15TDP1
	SCHEMBL29017541	0.88	DGKA (0.68)	DGKACYP1A2ALDH1A1TSHRDNM1
	SCHEMBL20210674	0.88	DGKA (0.57)	DGKACYP1A2ALDH1A1ALOX15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.