SCHEMBL849281

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13552101	0.86	MEN1 (0.51)	ALDH1A1KMT2AMEN1
	SCHEMBL848950	0.82	MEN1 (0.53)	ALDH1A1GAAKMT2AMEN1SMN1; SMN2
	SCHEMBL847618	0.81	MEN1 (0.46)	LMNAALDH1A1KMT2AMEN1HSD17B10
	SCHEMBL848594	0.81	MEN1 (0.46)	LMNAALDH1A1GAAL3MBTL1KMT2A
	SCHEMBL849183	0.79	TSHR (0.56)	LMNAALDH1A1GAAL3MBTL1KMT2A
	SCHEMBL849347	0.79	MEN1 (0.50)	MAPK1ALDH1A1KMT2AMEN1SMN1; SMN2
	SCHEMBL849240	0.78	MEN1 (0.48)	ALDH1A1GAAKMT2AMEN1SMN1; SMN2
	SCHEMBL848670	0.76	MEN1 (0.51)	ALDH1A1GAAKMT2AMEN1
	SCHEMBL848900	0.76	MEN1 (0.50)	MAPK1ALDH1A1GAAKMT2AMEN1
	SCHEMBL849742	0.76	KMT2A (0.46)	LMNAALDH1A1GAAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.