Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8493498 | 1.00 | ATM (0.57) | ATMALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL8496723 | 0.91 | MEN1 (0.50) | ATMALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL8496724 | 0.91 | MEN1 (0.50) | ATMALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL8498707 | 0.89 | ATM (0.44) | ATMALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL8498706 | 0.89 | ATM (0.44) | ATMALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL8499194 | 0.86 | KDM4E (0.47) | ATMALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL8499190 | 0.86 | KDM4E (0.47) | ATMALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL8498042 | 0.83 | ATM (0.59) | ATMALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL8498045 | 0.83 | ATM (0.59) | ATMALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL27487152 | 0.79 | MEN1 (0.42) | ATMALDH1A1MAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | disclosed |