Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498045 | 1.00 | ATM (0.59) | ATMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8498152 | 0.87 | G6PC1 (0.54) | ATMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8497911 | 0.86 | GAA (0.50) | ATMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8497909 | 0.86 | GAA (0.50) | ATMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8498487 | 0.85 | KDM4E (0.48) | ATMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8498485 | 0.85 | KDM4E (0.48) | ATMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8493502 | 0.83 | ATM (0.57) | ATMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8493498 | 0.83 | ATM (0.57) | ATMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8497057 | 0.78 | GAA (0.43) | ATMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8497059 | 0.78 | GAA (0.43) | ATMKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | disclosed |