Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 13/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ESRRG | P62508 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8496723 | 1.00 | MEN1 (0.50) | MEN1KMT2AATMESR1ESR2 | |
| SCHEMBL8493498 | 0.91 | ATM (0.57) | MEN1KMT2AATMESR1ESR2 | |
| SCHEMBL8493502 | 0.91 | ATM (0.57) | MEN1KMT2AATMESR1ESR2 | |
| SCHEMBL8498707 | 0.87 | ATM (0.44) | MEN1KMT2AATMLMNAMAPT | |
| SCHEMBL8498706 | 0.87 | ATM (0.44) | MEN1KMT2AATMLMNAMAPT | |
| SCHEMBL8499194 | 0.84 | KDM4E (0.47) | MEN1KMT2AATMLMNAMAPT | |
| SCHEMBL8499190 | 0.84 | KDM4E (0.47) | MEN1KMT2AATMLMNAMAPT | |
| SCHEMBL8497145 | 0.80 | MEN1 (0.52) | MEN1KMT2AATMESR1ESR2 | |
| SCHEMBL8497147 | 0.80 | MEN1 (0.52) | MEN1KMT2AATMESR1ESR2 | |
| SCHEMBL8496840 | 0.78 | G6PC1 (0.53) | MEN1KMT2AATMESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | disclosed |