Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | HPD | P32754 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MASP2 | O00187 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490798 | 0.88 | HPD (0.40) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL8492271 | 0.85 | MEN1 (0.41) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL8492171 | 0.84 | MAPT (0.42) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL8492169 | 0.84 | MEN1 (0.41) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL8488250 | 0.84 | KMT2A (0.39) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL8895023 | 0.82 | HPD (0.48) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL8896420 | 0.77 | HPD (0.48) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL8897035 | 0.76 | HPD (0.48) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL8894469 | 0.76 | HPD (0.48) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL8492588 | 0.75 | HPD (0.51) | MEN1KMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | claimed |
| EP-0470856-B1 | Isoxazole derivatives, process for their preparation and their herbicidal applications | RHONE POULENC AGRICULTURE (GB) | 1995-10-11 | — | — | EP | claimed |
| EP-0470856-A1 | Isoxazole derivatives, process for their preparation and their herbicidal applications | RHONE-POULENC AGRICULTURE LTD. (GB) | 1992-02-12 | — | — | EP | claimed |
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| EP-0470856-B1 | Isoxazole derivatives, process for their preparation and their herbicidal applications | RHONE POULENC AGRICULTURE (GB) | 1995-10-11 | — | — | EP | disclosed |
| EP-0470856-A1 | Isoxazole derivatives, process for their preparation and their herbicidal applications | RHONE-POULENC AGRICULTURE LTD. (GB) | 1992-02-12 | — | — | EP | disclosed |