Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895023 | 0.91 | HPD (0.48) | HPDMAPK1DHODHMAPTMEN1 | |
| SCHEMBL8896420 | 0.85 | HPD (0.48) | HPDMAPK1DHODHMAPTMEN1 | |
| SCHEMBL8490798 | 0.84 | HPD (0.40) | HPDMAPK1DHODHMAPTMEN1 | |
| SCHEMBL8894469 | 0.84 | HPD (0.48) | HPDMAPK1DHODHMAPTMEN1 | |
| SCHEMBL8492588 | 0.81 | HPD (0.51) | HPDMAPK1DHODHMAPTMEN1 | |
| SCHEMBL8495654 | 0.78 | HPD (0.53) | HPDMAPK1DHODHMAPTMEN1 | |
| SCHEMBL8489367 | 0.77 | HPD (0.52) | HPDMAPK1DHODHMAPTMEN1 | |
| SCHEMBL8492171 | 0.77 | MAPT (0.42) | HPDMAPK1DHODHMAPTMEN1 | |
| SCHEMBL8493548 | 0.76 | MEN1 (0.39) | HPDMAPK1DHODHMAPTMEN1 | |
| SCHEMBL8492271 | 0.76 | MEN1 (0.41) | HPDMAPK1DHODHMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |