Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.53 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.53 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.50 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490397 | 0.84 | NQO1 (0.69) | PDE2AESR2ESR1MAOAMAPT | |
| SCHEMBL3364138 | 0.81 | NQO1 (0.71) | MAOAMAPTKDM4EMEN1KMT2A | |
| Iodomethane SCHEMBL8494114 | 0.79 | HSD17B3 (0.64) | PDE2AESR2ESR1MAOAMAPT | |
| SCHEMBL8496689 | 0.79 | CSNK2A2 (0.53) | PDE2AESR2ESR1CYP3A4MAPT | |
| SCHEMBL8496607 | 0.79 | CSNK2A2 (0.53) | PDE2AESR2ESR1MAOACYP3A4 | |
| SCHEMBL10795110 | 0.78 | HSD17B3 (0.73) | PDE2AESR2ESR1MAOAKDM4E | |
| SCHEMBL11477219 | 0.78 | ERAP1 (0.61) | ESR2ESR1MAOACYP3A4MAPT | |
| SCHEMBL27879033 | 0.78 | ESR2 (0.61) | PDE2AESR2ESR1MAOACYP3A4 | |
| SCHEMBL31415974 | 0.77 | NPSR1 (0.74) | PDE2AESR2ESR1MAOAMAPT | |
| SCHEMBL7859223 | 0.77 | NPSR1 (0.74) | PDE2AESR2ESR1MAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598117-B1 | BENZOPYRAN DERIVATIVE AND ANTIALLERGIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | DAINIPPON INK & CHEMICALS (JP) | 1999-06-30 | — | — | EP | disclosed |
| US-5428059-A | Benzopyran derivatives and an anti-allergic agent possessing the same as the active ingredient | DAINIPPON INK & CHEMICALS, INC. (JP) | 1995-06-27 | — | — | US | disclosed |
| EP-0598117-A1 | BENZOPYRAN DERIVATIVE AND ANTIALLERGIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1994-05-25 | — | — | EP | disclosed |