SCHEMBL8494237

SCHEMBL8494237

CCCCC(CCS)CN(CCC)CCC

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
PLA2G1B P04054 1/20 0.33
PLA2G2A P14555 1/20 0.33
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8490026 0.92 ALDH1A1 (0.34) ALDH1A1TDP1CYP3A4TSHRPLA2G1B
SCHEMBL8491167 0.88
SCHEMBL8493318 0.86 PLA2G1B (0.42) ALDH1A1TDP1CYP3A4TSHRPLA2G1B
SCHEMBL8492624 0.86 ALDH1A1 (0.35) ALDH1A1TDP1CYP3A4TSHRPLA2G1B
SCHEMBL8490002 0.84 PLA2G1B (0.33) TDP1PLA2G1BPLA2G2A
SCHEMBL8493942 0.83 ALDH1A1 (0.31) ALDH1A1CYP3A4TSHR
SCHEMBL627254 0.81 ALDH1A1 (0.52) ALDH1A1TDP1CYP3A4TSHRPLA2G1B
SCHEMBL8490368 0.81 ALDH1A1 (0.38) ALDH1A1TDP1CYP3A4TSHRLMNA
SCHEMBL8493927 0.80 ALDH1A1 (0.38) ALDH1A1TDP1CYP3A4TSHRPLA2G1B
SCHEMBL28222390 0.79 PLA2G1B (0.44) ALDH1A1TDP1CYP3A4TSHRPLA2G1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0676237-B1 Modified ion exchange resins and use thereof MITSUBISHI CHEM CORP (JP) 1999-03-17 EP disclosed
US-5589517-A N,N-DI-SUBSTITITUTED MERCAPTOALKYLAMINE SULFONIC ACID ION EXCHANGE RESIN AS CATALYST FOR CONDENSATION REACTION OF A PHENOL AND A KETONE TO PRODUCE A BISPHENOL MITSUBISHI CHEMICAL CORPORATION (JP) 1996-12-31 US disclosed
EP-0676237-A1 Modified ion exchange resins and use thereof MITSUBISHI CHEMICAL CORPORATION (JP) 1995-10-11 EP disclosed