SCHEMBL849425

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15803682	0.81	AR (0.43)	ARTSHRPOLBALDH1A1NPSR1
	SCHEMBL849167	0.81	AR (0.52)	ARALKBH5TSHRPOLBALDH1A1
	SCHEMBL25248135	0.77	AR (0.49)	ARALKBH5POLBHPGDNPSR1
	SCHEMBL30382173	0.75	ALDH1A1 (0.51)	ARALKBH5POLBALDH1A1MEN1
	SCHEMBL25249887	0.75	ALDH1A1 (0.51)	ARALKBH5POLBALDH1A1MEN1
	SCHEMBL30381482	0.72	AR (0.69)	ARTSHR
	SCHEMBL25247254	0.72	AR (0.69)	ARTSHR
	SCHEMBL25248589	0.69	AR (0.57)	ARPOLBALDH1A1MEN1KMT2A
	SCHEMBL11838692	0.69	AR (0.53)	ARPOLBALDH1A1MEN1CYP1A2
	SCHEMBL849389	0.69	POLB (0.48)	ALKBH5TSHRPOLBALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.