Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | MIF | P14174 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | DNTT | P04053 | 3/20 | 0.37 |
| ▸ | POLA1 | P09884 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20645845 | 0.89 | MIF (0.48) | F10MIFHTTSMN1; SMN2LMNA | |
| SCHEMBL20645838 | 0.83 | MIF (0.50) | MIFHTTPOLBLMNARAB9A | |
| SCHEMBL20640879 | 0.79 | MIF (0.40) | F10MIFHTT | |
| SCHEMBL10758499 | 0.76 | MIF (0.42) | MIFHTT | |
| SCHEMBL20640544 | 0.76 | MIF (0.50) | MIFHTTPOLBLMNATSHR | |
| SCHEMBL25438280 | 0.72 | PSMB5 (0.43) | F10 | |
| SCHEMBL25438284 | 0.72 | PSMB5 (0.43) | F10 | |
| SCHEMBL12460807 | 0.71 | F10 (0.35) | F10 | |
| SCHEMBL12461518 | 0.71 | F10 (0.35) | F10 | |
| SCHEMBL8444142 | 0.71 | MIF (0.58) | MIFHTTPOLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701991-B1 | Process for the preparation of lignin analogues and starting materials therefor | SHIONOGI & CO (JP) | 1999-01-20 | — | — | EP | disclosed |
| US-5731455-A | ALKYL 2-ALKYLACYLACRYLATE CHEMICAL INTERMEDIATE; ANTICHOLESTEROL AGENTS | SHIONOGI & CO., LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0597107-B1 | LIGNAN ANALOG, PRODUCTION THEREOF, AND HYPOLIPIDEMIC DRUG | SHIONOGI & CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5502216-A | ANTICHOLESTEROL | SHIONOGI & CO., LTD. (JP) | 1996-03-26 | — | — | US | disclosed |
| EP-0701991-A1 | Process for the preparation of lignin analogues and starting materials therefor | SHIONOGI & CO., LTD. (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5449814-A | Dehydration; Michael condensation | SHIONOGI & CO., LTD. (JP) | 1995-09-12 | — | — | US | disclosed |
| US-5420333-A | Hydroxy ketone compounds | SHIONOGI & CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0597107-A1 | LIGNAN ANALOG, PRODUCTION THEREOF, AND HYPOLIPIDEMIC DRUG | SHIONOGI & CO., LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |