Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.42 |
| ▸ | MLYCD | O95822 | 10/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10756958 | 0.89 | MIF (0.36) | MIFMLYCDHTTCYP1A2CYP3A4 | |
| SCHEMBL10757347 | 0.89 | MIF (0.46) | MIFHTT | |
| SCHEMBL20645845 | 0.80 | MIF (0.48) | MIFHTTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL20645838 | 0.76 | MIF (0.50) | MIFHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8494420 | 0.76 | F10 (0.46) | MIFHTT | |
| SCHEMBL20640879 | 0.75 | MIF (0.40) | MIFHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20640544 | 0.73 | MIF (0.50) | MIFHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27526456 | 0.70 | HTT (0.48) | MIFHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8444142 | 0.68 | MIF (0.58) | MIFHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25399266 | 0.68 | ALDH1A1 (0.44) | MIFMLYCDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4677114-A | REDUCING AMNESIA, TREATMENT OF SENILITY | WARNER-LAMBERT COMPANY (US) | 1987-06-30 | — | — | US | disclosed |
| US-4677098-A | REDUCING AMNESIA AND TREATING SENILITY | WARNER-LAMBERT COMPANY (US) | 1987-06-30 | — | — | US | disclosed |