Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.47 |
| ▸ | ESRRG | P62508 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15658852 | 0.85 | PPARA (0.55) | NR4A2BLMSRD5A2LMNA | |
| SCHEMBL2442200 | 0.84 | EPHX2 (0.47) | SLC13A5EPHX2NR1H4ESRRGNR4A2 | |
| SCHEMBL27925093 | 0.83 | ESR1 (0.56) | PTGES2SMN1; SMN2BLMLMNA | |
| SCHEMBL27832630 | 0.82 | EPHX2 (0.45) | SLC13A5EPHX2NR1H4ESRRGNR4A2 | |
| SCHEMBL23582734 | 0.82 | MAPT (0.56) | SLC13A5EPHX2PTGES2SMN1; SMN2BLM | |
| SCHEMBL11596247 | 0.82 | BLM (0.67) | BLMCA2 | |
| SCHEMBL6668736 | 0.82 | BLM (0.52) | EPHX2ESRRGSMN1; SMN2BLMLMNA | |
| SCHEMBL4457891 | 0.82 | BLM (0.47) | PTGES2SMN1; SMN2BLMSRD5A2RAB9A | |
| SCHEMBL517462 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2BLMLMNA | |
| SCHEMBL5394972 | 0.80 | PPARG (0.49) | PTGES2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863899-A | ANALGESICS AND ANTIINFLAMMATORY AGENT; A MORPHINE OR DERIVATIVE IS ATTACHED TO BRANDYKININ ANTAGONIST PEPTIDE BY MALEIMIDO OR AMINO ACID ANALOG LINKER | CORTECH, INC. (US) | 1999-01-26 | — | — | US | disclosed |