Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8494675 | 0.87 | NR1H4 (0.38) | NR1H4NPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL8487786 | 0.87 | NR1H4 (0.39) | NR1H4NPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL8525429 | 0.84 | NR1H4 (0.40) | NR1H4SMN1; SMN2HSP90AA1HTT | |
| SCHEMBL8491675 | 0.83 | NR1H4 (0.36) | NR1H4ALDH1A1KDM4EHSP90AA1HTT | |
| SCHEMBL8486767 | 0.82 | NR1H4 (0.41) | NR1H4NPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL8524086 | 0.82 | NR1H4 (0.40) | NR1H4NPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL8525752 | 0.82 | NR1H4 (0.41) | NR1H4NPC1ALDH1A1HSP90AA1HTT | |
| SCHEMBL8491830 | 0.81 | NR1H4 (0.40) | NR1H4ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL8487140 | 0.80 | HTT (0.43) | NR1H4ALDH1A1HPGDHTT | |
| SCHEMBL8488625 | 0.79 | NPC1 (0.40) | NPC1ALDH1A1KDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |