Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 13/20 | 1.00 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8495184 | 1.00 | G6PC1 (1.00) | G6PC1TRPM8MEN1ALDH1A1KMT2A | |
| SCHEMBL8498545 | 0.94 | G6PC1 (0.88) | G6PC1TRPA1LTA4H | |
| SCHEMBL8498548 | 0.94 | G6PC1 (0.88) | G6PC1TRPA1LTA4H | |
| SCHEMBL14799715 | 0.87 | G6PC1 (0.92) | G6PC1MEN1ALDH1A1KMT2AMCL1 | |
| SCHEMBL14799714 | 0.87 | G6PC1 (0.92) | G6PC1MEN1ALDH1A1KMT2AMCL1 | |
| SCHEMBL8498660 | 0.86 | G6PC1 (0.74) | G6PC1MEN1KMT2ALTA4H | |
| SCHEMBL8498656 | 0.86 | G6PC1 (0.74) | G6PC1MEN1KMT2ALTA4H | |
| SCHEMBL8498157 | 0.84 | G6PC1 (0.72) | G6PC1TRPM8MEN1ALDH1A1KMT2A | |
| SCHEMBL8498156 | 0.84 | G6PC1 (0.72) | G6PC1TRPM8MEN1ALDH1A1KMT2A | |
| SCHEMBL8499080 | 0.83 | G6PC1 (1.00) | G6PC1MEN1ALDH1A1KMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | claimed |
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | disclosed |