Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | C1R | P00736 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | F7 | P08709 | 2/20 | 0.44 |
| ▸ | F3 | P13726 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915806 | 0.83 | HSD17B10 (0.67) | ALDH1A1HPGDMEN1KMT2AF2 | |
| SCHEMBL915753 | 0.82 | ALDH1A1 (0.65) | ALDH1A1HPGDKMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL8496538 | 0.82 | F7 (0.49) | ALDH1A1HPGDMEN1KMT2AF2 | |
| SCHEMBL915773 | 0.80 | C1R (0.73) | MEN1KMT2AF2APEX1ELANE | |
| SCHEMBL913737 | 0.70 | C1R (0.57) | MEN1KMT2AF2APEX1ELANE | |
| SCHEMBL913374 | 0.69 | ALDH1A1 (1.00) | ALDH1A1HPGDMEN1KMT2AF2 | |
| SCHEMBL17554083 | 0.68 | APEX1 (0.76) | MEN1KMT2AF2APEX1ELANE | |
| SCHEMBL5921477 | 0.67 | ALDH1A1 (1.00) | ALDH1A1HPGDMEN1KMT2AF2 | |
| SCHEMBL30884604 | 0.67 | C1R (1.00) | ALDH1A1HPGDMEN1KMT2AF2 | |
| SCHEMBL915734 | 0.67 | C1R (1.00) | ALDH1A1HPGDMEN1KMT2AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999048878-A1 | HETEROCYCLIC COMPOUNDS REGULATING CLOTTING | NOVO NORDISK A/S (DK) | 1999-09-30 | — | — | WO | disclosed |