Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 2/20 | 0.49 |
| ▸ | F3 | P13726 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | C1R | P00736 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8495301 | 0.82 | ALDH1A1 (0.50) | F7F3KDM4EMAPTGAA | |
| SCHEMBL8070379 | 0.72 | KDM4E (0.75) | KDM4EMAPTGAAHSD17B10MAPK1 | |
| SCHEMBL914361 | 0.72 | C1R (0.74) | F7F3KDM4EMAPTGAA | |
| SCHEMBL914071 | 0.71 | C1R (0.61) | F7F3KDM4EMAPTGAA | |
| SCHEMBL17554098 | 0.70 | APEX1 (0.67) | F7F3KDM4EMAPTGAA | |
| SCHEMBL914239 | 0.70 | KDM4E (0.67) | F7F3KDM4EMAPTGAA | |
| SCHEMBL8059761 | 0.70 | MAPK1 (0.72) | KDM4EMAPTGAAHSD17B10MAPK1 | |
| SCHEMBL915758 | 0.70 | F7 (1.00) | F7F3KDM4EMAPTHSD17B10 | |
| SCHEMBL914467 | 0.69 | C1R (0.67) | F7F3MAPTC1RKMT2A | |
| SCHEMBL914657 | 0.68 | F7 (0.81) | F7F3KDM4EC1RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999048878-A1 | HETEROCYCLIC COMPOUNDS REGULATING CLOTTING | NOVO NORDISK A/S (DK) | 1999-09-30 | — | — | WO | disclosed |