Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.76 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.76 |
| ▸ | RAB9A | P51151 | 8/20 | 0.68 |
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.63 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.63 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8493681 | 0.89 | RAB9A (0.76) | SMN1; SMN2ALOX12RAB9ANPC1THRB | |
| SCHEMBL16566467 | 0.84 | RAB9A (0.72) | SMN1; SMN2ALOX12RAB9ANPC1KDM4E | |
| SCHEMBL31614553 | 0.82 | RAB9A (1.00) | SMN1; SMN2ALOX12RAB9ANPC1KDM4E | |
| SCHEMBL8491865 | 0.81 | RAB9A (1.00) | SMN1; SMN2ALOX12RAB9ANPC1THRB | |
| SCHEMBL18292315 | 0.77 | ALDH1A1 (1.00) | SMN1; SMN2ALOX12RAB9ANPC1KDM4E | |
| SCHEMBL9126856 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2ALOX12RAB9ANPC1THRB | |
| SCHEMBL8496098 | 0.75 | RAB9A (0.71) | SMN1; SMN2ALOX12RAB9ANPC1KDM4E | |
| SCHEMBL8495765 | 0.75 | RAB9A (0.71) | SMN1; SMN2RAB9ANPC1THRBALDH1A1 | |
| SCHEMBL11504808 | 0.75 | NOX1 (0.77) | SMN1; SMN2ALOX12RAB9ANPC1THRB | |
| SCHEMBL18617879 | 0.75 | RAB9A (0.83) | SMN1; SMN2ALOX12RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999011621-A2 | THIOUREA FOR INCREASING HDL-CHOLESTEROL LEVELS, WHICH ARE USEFUL AS ANTI-ATHEROSCLEROTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-03-11 | — | — | WO | claimed |
| WO-1999011621-A2 | THIOUREA FOR INCREASING HDL-CHOLESTEROL LEVELS, WHICH ARE USEFUL AS ANTI-ATHEROSCLEROTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-03-11 | — | — | WO | disclosed |