SCHEMBL8495495

SCHEMBL8495495

CC(N)C(C)(c1ccccc1)N(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.36
CYP2D6 P10635 2/20 0.35
CYP1A2 P05177 1/20 0.35
KCNN4 O15554 2/20 0.34
MAPK1 P28482 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 3/20 0.33
KIF11 P52732 2/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SLC6A2 P23975 2/20 0.32
MAOA P21397 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP2A6 P11509 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24399780 0.84 CYP2D6 (0.37) TAAR1CYP2D6CYP1A2KCNN4MAPK1
SCHEMBL19783840 0.70 TAAR1 (0.44) TAAR1CYP2D6CYP1A2KCNN4MAPK1
SCHEMBL25502576 0.70 TAAR1 (0.44) TAAR1CYP2D6CYP1A2KCNN4MAPK1
SCHEMBL20999978 0.70 TAAR1 (0.44) TAAR1CYP2D6CYP1A2KCNN4MAPK1
SCHEMBL2038162 0.70 KCNN4 (0.42) TAAR1KCNN4MAPK1MAPTKMT2A
SCHEMBL27668560 0.69 CYP2D6 (0.38) CYP2D6CYP1A2KCNN4MAPK1KMT2A
SCHEMBL8061599 0.69 KCNN4 (0.41) TAAR1CYP2D6KCNN4MAPK1MAPT
SCHEMBL3390152 0.69 RIPK1 (0.38) TAAR1CYP2D6CYP1A2MAPK1KMT2A
SCHEMBL1751596 0.69 MAPK1 (0.46) TAAR1CYP2D6CYP1A2KCNN4MAPK1
SCHEMBL4855348 0.68 KCNN4 (0.43) TAAR1CYP2D6CYP1A2KCNN4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5919608-A EXPOSING TO ELECTROMAGNETIC RADIATION A COMPOSITION COMPRISING CATIONIC ELECTRON ACCEPTOR, SENSITIZING DYE, AND SUPERSENSITIZER POLAROID CORPORATION (US) 1999-07-06 US disclosed