SCHEMBL3390152

SCHEMBL3390152

CC(C)C(C)(C)N(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 2/20 0.38
SMN1; SMN2 Q16637 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
AOC3 Q16853 1/20 0.35
HTT P42858 1/20 0.34
NPSR1 Q6W5P4 2/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
MLYCD O95822 1/20 0.32
ESR1 P03372 1/20 0.32
TRPA1 O75762 1/20 0.31
CACNA1F O60840 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24399780 0.76 CYP2D6 (0.37) RIPK1SMN1; SMN2MEN1KMT2ACYP3A4
SCHEMBL45354 0.74 MEN1 (0.40) SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9
SCHEMBL2119818 0.74 MEN1 (0.40) SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9
SCHEMBL12721861 0.74 MEN1 (0.40) SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9
SCHEMBL14151715 0.73 RIPK1 (0.32) RIPK1SMN1; SMN2MEN1KMT2ACYP3A4
SCHEMBL22294675 0.73 RIPK1 (0.32) RIPK1SMN1; SMN2MEN1KMT2ACYP3A4
SCHEMBL22903602 0.71 TSHR (0.36) RIPK1SMN1; SMN2MEN1KMT2ACYP3A4
SCHEMBL9701108 0.70 TAAR1 (0.41) SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9
SCHEMBL4265847 0.70 MEN1 (0.38) SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9
SCHEMBL28625822 0.69 TSHR (0.37) CYP3A4CYP2C19ALDH1A1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11065205-B2 Immediate/delayed drug delivery DRUG DELIVERY INTERNATIONAL LIMITED (GB) 2021-07-20 US claimed
US-20190125679-A1 IMMEDIATE/DELAYED DRUG DELIVERY UNIVERSITY OF STRATHCLYDE (GB) 2019-05-02 US claimed
EP-2542228-B1 PULSATILE DRUG RELEASE UNIV STRATHCLYDE (GB) 2017-11-29 EP claimed
EP-2542227-B1 IMMEDIATE/DELAYED DRUG DELIVERY UNIV STRATHCLYDE (GB) 2017-11-22 EP claimed
EP-2542226-B1 DELAYED PROLONGED DRUG DELIVERY UNIV STRATHCLYDE (GB) 2017-11-22 EP claimed
US-9474719-B2 Pulsatile drug release UNIVERSITY OF STRATHCLYDE (GB) 2016-10-25 US claimed
US-9283192-B2 Delayed prolonged drug delivery UNIVERSITY OF STRATHCLYDE (GB) 2016-03-15 US claimed
US-20100144657-A1 PHENYLPIPERIDINE MODULATORS OF mu-OPIOID RECEPTORS AUSPEX PHARMACEUTICALS, INC. (US) 2010-06-10 US claimed
US-20250312396-A1 Control of Cellular Redox Levels MCKENNA ELIZABETH (US) 2025-10-09 US disclosed
US-20250114411-A1 SOLID DOSAGE FORMS CONTAINING BACTERIA AND MICROBIAL EXTRACELLULAR VESICLES EVELO BIOSCIENCES INC (US) 2025-04-10 US disclosed
US-12268718-B2 Control of cellular redox levels LABYRINTH HOLDINGS LLC 2025-04-08 US disclosed
WO-2024197124-A9 ARGININE VASOPRESSIN RECEPTOR (AVPR) ANTAGONISTS AND METHODS OF USING THEREOF UNIVERSITY OF MIAMI (US) 2024-12-19 WO disclosed
EP-4404921-A1 SOLID DOSAGE FORMS CONTAINING BACTERIA AND MICROBIAL EXTRACELLULAR VESICLES Evelo Biosciences, Inc. (US) 2024-07-31 EP disclosed
US-20230355689-A1 SOLID DOSAGE FORMS CONTAINING BACTERIA AND MICROBIAL EXTRACELLULAR VESICLES EVELO BIOSCIENCES, INC. 2023-11-09 US disclosed
EP-2983657-A1 TREATMENT OF GASTROINTESTINAL AND OTHER DISORDERS Numedii, Inc. (US) 2016-02-17 EP disclosed
EP-2699579-B1 PYRAZOLO[4,3-D]PYRIMIDINES USEFUL AS KINASE INHIBITORS ORIGENIS GMBH (DE) 2015-10-07 EP disclosed
WO-2014165823-A1 TREATMENT OF GASTROINTESTINAL AND OTHER DISORDERS NUMEDII, INC. (US) 2014-10-09 WO disclosed
US-20120329785-A1 Novel kinase inhibitors ORIGENIS GMBH (DE) 2012-12-27 US disclosed
US-20120329780-A1 Novel kinase inhibitors ORIGENIS GMBH (DE) 2012-12-27 US disclosed
US-20100144657-A1 PHENYLPIPERIDINE MODULATORS OF mu-OPIOID RECEPTORS AUSPEX PHARMACEUTICALS, INC. (US) 2010-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100144657-A1 PHENYLPIPERIDINE MODULATORS OF mu-OPIOID RECEPTORS OPRM1, OPRK1, OPRD1 RIPK1 3455/4885SMN1; SMN2 2559/4885MEN1 4878/4885
US-20120329780-A1 Novel kinase inhibitors LRRK2, MYLK2, MYLK RIPK1 225/4885SMN1; SMN2 882/4885MEN1 544/4885
US-20120329785-A1 Novel kinase inhibitors LRRK2, MYLK2, MYLK3 RIPK1 170/4885SMN1; SMN2 609/4885MEN1 2656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.