Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | OGA | O60502 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PYGB | P11216 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MANBA | O00462 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SLC28A3 | Q9HAS3 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5666062 | 1.00 | GBA1 (0.47) | GBA1LMNAOGATSHRPYGB | |
| SCHEMBL4207953 | 0.94 | GBA1 (0.55) | GBA1LMNAOGATSHRPYGB | |
| SCHEMBL9297697 | 0.94 | GBA1 (0.55) | GBA1LMNAOGATSHRPYGB | |
| SCHEMBL321985 | 0.94 | GBA1 (0.55) | GBA1LMNAOGATSHRPYGB | |
| SCHEMBL18427840 | 0.79 | OGA (0.45) | GBA1LMNAOGATSHRPYGB | |
| SCHEMBL3675624 | 0.74 | GBA1 (0.55) | GBA1LMNAOGATSHRPYGB | |
| SCHEMBL7826551 | 0.72 | OGA (0.42) | GBA1LMNAOGATSHRGAA | |
| SCHEMBL5162383 | 0.71 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL668693 | 0.71 | GBA1 (0.50) | GBA1LMNAOGATSHRPYGB | |
| SCHEMBL17978030 | 0.71 | GBA1 (0.50) | GBA1LMNAOGATSHRPYGB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861503-A | FLUORINATING WITH FLUORINE OR ACETYL HYPOFLUORITE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-01-19 | — | — | US | disclosed |
| US-5646125-A | Polysubstituted benzimidazoles as antiviral agents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1997-07-08 | — | — | US | disclosed |
| EP-0354180-A2 | Certain imidazo[4,5-b]pyridine derivatives | CIBA-GEIGY AG (CH) | 1990-02-07 | — | — | EP | disclosed |