Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MANBA | O00462 | 1/20 | 0.40 |
| ▸ | PYGB | P11216 | 9/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4207953 | 0.81 | GBA1 (0.55) | GBA1LMNAOGAGAAMANBA | |
| SCHEMBL321985 | 0.81 | GBA1 (0.55) | GBA1LMNAOGAGAAMANBA | |
| SCHEMBL9297697 | 0.81 | GBA1 (0.55) | GBA1LMNAOGAGAAMANBA | |
| SCHEMBL5666062 | 0.74 | GBA1 (0.47) | GBA1LMNAOGAGAAMANBA | |
| SCHEMBL8495531 | 0.74 | GBA1 (0.47) | GBA1LMNAOGAGAAMANBA | |
| Gluconolactone SCHEMBL24637666 | 0.71 | LMNA (1.00) | GBA1LMNAOGAGAAMANBA | |
| Gluconolactone SCHEMBL13176828 | 0.71 | LMNA (1.00) | GBA1LMNAOGAGAAMANBA | |
| Gluconolactone SCHEMBL12377168 | 0.71 | LMNA (1.00) | GBA1LMNAOGAGAAMANBA | |
| Gluconolactone SCHEMBL17831964 | 0.71 | LMNA (1.00) | GBA1LMNAOGAGAAMANBA | |
| Gluconolactone SCHEMBL2461264 | 0.71 | LMNA (1.00) | GBA1LMNAOGAGAAMANBA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162153-A1 | DIETARY SUPPLEMENTS FOR PROMOTION OF GROWTH, REPAIR, AND MAINTENANCE OF BONE AND JOINTS | Novus International, Inc. (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008154178-A1 | DIETARY SUPPLEMENTS FOR PROMOTION OF GROWTH, REPAIR, AND MAINTENANCE OF BONE AND JOINTS | NOVUS INTERNATIONAL INC. (US) | 2008-12-18 | — | — | WO | disclosed |