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Sugi Predict / Compounds / SCHEMBL9297697

SCHEMBL9297697

SCHEMBL9297697

CC(=O)[C]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GBA1 P04062 2/20 0.55
▸ LMNA P02545 1/20 0.55
▸ OGA O60502 7/20 0.47
▸ TSHR P16473 1/20 0.41
▸ GAA P10253 2/20 0.40
▸ MANBA O00462 1/20 0.40
▸ PYGB P11216 5/20 0.38
▸ SLC28A3 Q9HAS3 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL321985 1.00 GBA1 (0.55) GBA1LMNAOGATSHRGAA
SCHEMBL4207953 1.00 GBA1 (0.55) GBA1LMNAOGATSHRGAA
SCHEMBL8495531 0.94 GBA1 (0.47) GBA1LMNAOGATSHRGAA
SCHEMBL5666062 0.94 GBA1 (0.47) GBA1LMNAOGATSHRGAA
SCHEMBL18427840 0.81 OGA (0.45) GBA1LMNAOGATSHRGAA
SCHEMBL3675624 0.81 GBA1 (0.55) GBA1LMNAOGATSHRGAA
SCHEMBL17978030 0.77 GBA1 (0.50) GBA1LMNAOGATSHRGAA
SCHEMBL668693 0.77 GBA1 (0.50) GBA1LMNAOGATSHRGAA
SCHEMBL5162383 0.74 SMN1; SMN2 (0.37) —
Gluconolactone SCHEMBL24637666 0.71 LMNA (1.00) GBA1LMNAOGAGAAMANBA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0596929-A1 AMIDE DERIVATIVES OF ANTIBIOTIC A 40926. LEPETIT SPA (IT) 1994-05-18 — — EP claimed
WO-1993003060-A1 AMIDE DERIVATIVES OF ANTIBIOTIC A 40926 GRUPPO LEPETIT S.P.A. (IT) 1993-02-18 — — WO claimed
WO-1993003060-A1 AMIDE DERIVATIVES OF ANTIBIOTIC A 40926 GRUPPO LEPETIT S.P.A. (IT) 1993-02-18 — — WO disclosed